Clinical Studies


Efficacy of a dual-ring wound protector for prevention of surgical site infections after pancreaticoduodenectomy in patients with intrabiliary stents: A randomized clinical trial

Published: Annals of Surgery; 2018 July
Authors: Bressan AK, Aubin J-M, Martel G, Dixon E, Bathe OF, Sutherland FR, Balaa F, Mimeault R, Edwards JP, Grondin SC, Isherwood S, Lillemoe KD, Saeed S, Ball CG
Excerpt: “Among adult patients with intrabiliary stents, the use of a dual-ring wound protector during [pancreaticoduodenectomy] significantly reduces the risk of incisional SSI.”
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Wound protectors in reducing surgical site infections in lower gastrointestinal surgery: An updated meta-analysis

Published: Surgical Endoscopy; 2018 March
Authors: Zhang L, Elsolh B, Patel SV
Excerpt: “Our meta-analysis found that dual-ring wound protectors reduce the odds of SSI in patients undergoing lower gastrointestinal surgery.”
“We demonstrated evidence of a subgroup difference where dual-ring wound protectors reduced SSIs while single-ring retractors did not, which provides greater insight in the choice of wound protection devices.”
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Wound Protectors Reduce Surgical Site Infection: A Meta-Analysis of Randomized Controlled Trials

Published: Annals of Surgery; 2012 July
Authors: Edwards JP, Ho AL, Tee MC, Dixon E, Ball CG
Excerpt: "Impervious plastic wound protectors reduce the risk of SSI when employed in non-trauma-related gastrointestinal and biliary tract surgery. Wound protectors represent a safe and simple intervention that may reduce postoperative morbidity and mortality."
"Our study suggests that the use of wound protectors decreases the risk of SSI by 45%. Our number needed to treat suggests that only 10 patients would have to be treated intraoperatively with a wound protector to prevent 1 SSI."
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Plastic wound retractors as bacteriological barriers in gastrointestinal surgery: a prospective multi-institutional trial

Published: Journal of Hospital Infection; 2012 June
Authors: Mohan HM, McDermott S, Fenelon L, Fearon NM, O'Connell PR, Oon SF, Burke J, Keane E, Shields C, Winter DC; Members of the University College Dublin Wound Retractor Study Group
Excerpt: "In summary, use of a plastic wound retractor may result in reduced enteric bacterial colonization of the surgical incision site during gastrointestinal surgery. Reduced colonization of the surgical incision site by enteric bacteria due to the use of a plastic wound retractor should result in a reduction in SSI following gastrointestinal surgery."
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ALEXIS O-Ring wound retractor vs conventional wound protection for the prevention of surgical site infections in colorectal resections

Published: Colorectal Disease; 2012 June
Authors: Cheng KP, Roslani AC, Sehha N, Kueh JH, Law CW, Chong HY, Arumugam K
Excerpt: "The ALEXIS wound retractor is more effective in preventing SSI in elective colorectal resections compared with conventional methods."
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A Wound Protector Shields Incision Sites from Bacterial Invasion

Published: Surgical Infections; 2010 December
Authors: Horiuchi T, Tanishima H, Tamagawa K, Sakaguchi S, Shono Y, Tsubakihara H, Tabuse K, Kinoshita Y
Excerpt: "These results suggest that the [wound protector] protects an incision site from bacterial invasion."
"[W]e consider that the low incidence of SSI may have resulted from the protective effects of the [wound protector]."
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Barrier Wound Protection Decreases Surgical Site Infection in Open Elective Colorectal Surgery: A Randomized Clinical Trial

Published: Diseases of the Colon & Rectum; 2010 October
Authors: Reid K, Pockney P, Draganic B, Smith SR
Excerpt: "In this study the use of barrier wound protection in elective open colorectal resectional surgery resulted in a clinically significant reduction in incisional surgical site infections. Barrier wound protection of this nature should be considered routine in this type of surgery."
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Use of Wound-Protection System and Postoperative Wound-Infection Rates in Open Appendectomy

Published: Archives of Surgery; 2009 September
Authors: Lee P, Waxman K, Taylor B, Yim S
Excerpt: "Our data support the use of a wound-protection device in open surgery as a method of decreasing postoperative wound-infection rates. This technique could be applied to a broader spectrum of open surgical procedures and ultimately reduce the economic and emotional burden of a preventable SSI."
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A wound retractor/protector can prevent infection by keeping tissue moist and preventing tissue damage at incision sites

Published: Helix Review Series: Infectious Diseases; 2007
Authors: Horiuchi T, Nakatsuka S, Tanishima H, Tamagawa K, Shono Y, Tsubakihara H, Inoue M, Tabuse K
Excerpt: "We found that the wound retractor/protector prevented the incision site from drying, decreased tissue damage, and facilitated the migration of neutrophils, suggesting a preventive effect of the device with respect to wound infection."
"The studied wound retractor/protector effectively protects wound tissue from damage due to environmental factors experienced during surgery."
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Randomized, Controlled Investigation of the Anti-Infective Properties of the Alexis Retractor/Protector of Incision Sites

Published: The Journal of Trauma-Injury & Critical Care; 2007 January
Authors: Horiuchi T, Tanishima H, Tamagawa K, Matsuura I, Nakai H, Shouno Y, Tsubakihara H, Inoue M, Tabuse K
Excerpt: "The results of this study demonstrate that wound infection decreased significantly in the With Alexis retractor group."
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